Allen Cells in LSCBE
Cell lines listed in grant:
for the below cell lines please contact Mika Katsura and Susanne Meyer.
| Cell Line | Modification | Source | |
| 1. | H9 hESC | b-catenin-tdmruby opto-LRP6 (controlling WNT signaling) | Wilson |
| 2. | H9 hESC | b-catenin-tdmruby (visualizing WNT signaling) | Wilson |
| 3. | H9 hESC | OptoSOS (controlling Erk signaling) | Wilson |
| 4. | H9 hESC | Erk-KTR (visualizing Erk signaling) | Wilson |
| 5. | WTC-11 iPSC | Dox-inducible Cas9-BFP at the AAVS1 locus with stable expression of the following guides: Guide targeting the AluGG region in Alu elements (causes many double stranded DNA breaks) | Richardson |
| 6. | WTC-11 iPSC | Guide that targets the Transthyretin (TTR) gene (Transthyretin Amyloidosis) | Richardson |
| 7. | WTC-11 iPSC | Guide that targets the Huntingtin (HTT) gene near the repeat expansion locus. (Huntington’s Disease) | Richardson |
| 8. | WTC-11 iPSC | Guide that targets the beta globulin HBB gene, which cuts near the E6V disease locus (Sickle Cell Disease) | Richardson |
| 9. | WTC-11 iPSC | Guide that targets the Lamin B1 (LMNB1) gene and cuts near the start codon (autosomal dominant leukodystrophy with autonomic disease (ADLD) | Richardson |
| 10. | WTC-11 iPSC | Parental line / dox-inducible Cas9-BFP at AAVS1 locus. | Richardson |
| 11. | ND32951A iPSC | MAPT mutation V337M/WT (FTLD-tau) | Kosik |
| 12. | ND32951AciPSC | CRSPR corrected WT/WT from above | Kosik |
| 13. | FTD19 iPSC | MAPT mutation A152T/WT (FTLD-tau) | Kosik |
| 14. | TDP43 iPSC | TDP43 mutation iPSC (Alzheimer’s Disease) | Kosik |
| 15. | APOE iPSC | APOE isoforms iPSC (Alzheimer’s Disease) | Kosik |
| 16. | PSEN iPSC | PSEN mutant iPSC (Alzheimer’s Disease) | Kosik |
| 17. | Cri du chat Syndrome iPSC | Disease causing deletion on Chromosome 5 (CdC Syndrome) | Kosik |
| 18. | Williams iPSC | Disease causing mutations (Williams Syndrome) | Kosik |
| 19. | CRISPRi Line90 (from WTC-11 iPSC) | Both alleles of the NineTeen Complex (NTC) gene (spliceosome, DNA repair functions) | Richardson |
| 20. | CRISPRi Line90 | Both alleles of the AXIN1 gene (WNT signaling, Meduloblastoma) | Richardson |
| 21. | CRISPRi Line90 | Both alleles of the RNF146 gene (WNT signaling) | Richardson |
| 22. | CRISPRi Line90 | Both alleles of the PEX14 gene (Peroxisomal Import; Zellweger Syndrome) | Richardson |
| 23. | CRISPRi Line90 | Both alleles of the PEX19 gene (Peroxisomal Import; Zellweger Syndrome) | Richardson |
| 24. | CRISPRi Line90 | Both alleles of the PEX1 gene (Peroxisomal Import; Zellweger Syndrome) | Richardson |
| 25. | CRISPRi Line90 | Both alleles of the PEX6 gene (Peroxisomal Import; Zellweger Syndrome) | Richardson |
| 26. | TYR H9 hESC | H9 Tyrosinase catalytic inactive mutant S380P (AMD) | Clegg |
| 27. | hESC-RPE | Differentiated RPE from H9 hESC (AMD) | Clegg |
| 28. | PRPF8 iPSC | Patient-derived PRPF8 iPSC (Retinitis Pigmentosa) | Clegg |
| 29. | PRPF8c iPSC | CRSPR-corrected PRPF8 iPSC (Retinitis Pigmentosa) | Clegg |
| 30. | LAMP2B H9 hESC | CRSPR-CAS9 engineered H9 hESC LAMP2B knockout (Danons Disease) | Clegg |
| 31. | LAMP2 iPSC | Patient-derived Danon Disease iPSC (LAMP2 -/-) | Clegg |
| 32. | RhoP23H iPSC | Patient-derived Rhodopsin P23H (Retinitis Pigmentosa) | Clegg |
| 33. | Rhodopsin P23H H9 hESC | CRSPR-CAS9 engineered H9 Rhodopsin P23H (Retinitis Pigmentosa) | Clegg |
| 34. | from WTC-11 | 56 Allen Institute cell lines with fluorescent reporters | Meyer |
